Soy and cancer PART 1
In 1997, researchers in the cancer field were excited as hell when Judah Folkman and collaborators at Harvard University, USA, have notified the discovery of a substance that could make tumors in mice disappear.
As a surgeon at Children’s Hospital Boston, Folkman has worked hard to combat cancer, using the blood flow that diminish method that reaches the tumor, thus avoiding poisoning the patients with chemotherapy. Was pursuing for the blood vessels atrophy that feeds the tumor. Using a substance called endostatin the group of researchers from Harvard earned spectacular results, followed by clinical experiments.
But researchers who have tried to use the method of Folkman have managed to observe the endostatin miraculous properties. Recently, two published studies in the april issue 2002 of Molecular Therapy magazine, shows that endostatin has no effect on tumors in mice. Furthermore, endostatin was tested in nearly 200 patients, without getting any single healing.
When, in 1997, Michael O’Reilly and Folkman described endostatin for first time, seemed an ideal anticancer weapon. The toxic substance made to disappear, selectively, tumors blood vessels, causing them to atrophy until microscopic dimensions.
Seeing the results published, James Watson, Nobel Prize winner said excitedly that “in two years, Folkman would cure malignant tumors “. Dr. Folkman became the hero of a book published in 2001. The substance that was promising to stop the development off blood vessels that are supplying tumors became the subject of innumerable researches, which, unfortunately, could not confirm the results published five years earlier.
Still seems that, with all the advanced technology, the most effective weapon against cancer remains the prevention or prophylaxis through the lifestyle for which we decide.
It is true that, at the moment, in most industrial countries, cardiovascular diseases are first among causes of death, the main culprit being myocardial infarction. But in some countries, due to the decline in the numbers of smokers and animal fats consumption diminish, cardiovascular diseases are decreasing. We can’t say the same thing about cancerous diseases. In England, for example, the number of cancer deaths has come to overcome the myocardial infarction. Half of mortality from cancers is due to following four localization: lung, large intestine, breast and prostate. Interestingly, virtually, these cancers are absent in many countries of the third world, but their frequency increases rapidly during the first or second generation, by the emigration of those from regions with a low risk of malignancy in regions with a higher risk.
Many of the common malignancies in are due to environmental factors, and these are preventable. alimentation is the most important lifestyle factor. Nutrition is responsible for 80% of cancers of the colon, breasts and prostate. Even lung cancer can have a food component in its emergence, although smoking is the main factor. Smokers should know that tobacco contributes in the emergence of malignant tumors of the oral cavity, pharynx, larynx, esophagus, stomach, pancreas and bladder.
Cancer occurs usually after one or more mutations in deoxyribonucleic acid, which makes up the genes. These mutations can be inherited or acquired during lifetime. Eg. in breast cancer, BRCA1 and BRCA2 mutations in genes confers an increased risk for breast cancer and ovarian cancer, however, practically, these genes are only responsible for 2-3% in the cases of this malignancies.